INDICATIONS AND DOSING INFORMATION

1. To reduce the combined risk of death and nonfatal stroke in patients who have had ischemic stroke or transient ischemia of the brain due to fibrin platelet emboli
2. To reduce the risk of vascular mortality in patients with a suspected acute myocardial infarction (MI)
3. To reduce the combined risk of death and nonfatal MI in patients with a previous MI or unstable angina pectoris
4. To reduce the combined risk of MI and sudden death in patients with chronic stable angina pectoris
5. In patients who have undergone revascularization procedures (eg, coronary artery bypass graft [CABG], percutaneous transluminal coronary angioplasty [PTCA] or carotid endarterectomy [CEA]) when there is a preexisting condition for which aspirin is already indicated
6. For the relief of the signs and symptoms of rheumatoid arthritis, juvenile rheumatoid arthritis, osteoarthritis, spondyloarthropathies, and arthritis and pleurisy associated with systemic lupus erythematosus

Each dose of aspirin should be taken with a full glass of water, unless patient is fluid restricted. Anti-inflammatory and analgesic dosages should be individualized. When aspirin is used in high doses, the development of tinnitus may be used as a clinical sign of elevated plasma salicylate levels except in patients with high frequency hearing loss.