Every 40 seconds
an American has a heart attack or stroke. And after a primary CV event, the risk for recurrent events increases.7,8
STUDIES SHOW THAT
STUDIES ALSO SHOW THAT
*Nonfatal myocardial infarction or ischemic stroke.
†A cross-sectional analysis of a representative sample, 3599 US adults aged ≥40 years from the National Health and Nutrition Examination Survey.10
‡In a meta-analysis of 6300 patients.11
References: 1. Antithrombotic Trialists’ (ATT) Collaboration. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009;373(9678):1849-1860. 2. García Rodríguez LA, Cea-Soriano L, Martín-Merino E, Johansson S. Discontinuation of low dose aspirin and risk of myocardial infarction: case-control study in UK primary care. BMJ. 2011;343:d4094. doi:10.1136/bmj.d4094 3. García Rodríguez LA, Cea Soriano L, Hill C, Johansson S. Increased risk of stroke after discontinuation of acetylsalicylic acid: a UK primary care study. Neurology. 2011;76(8):740-746. doi:10.1212/WNL.0b013e31820d62b5 4. Plavix® (clopidogrel bisulfate). Prescribing information. Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership; 2021. 5. Brilinta® (ticagrelor). Prescribing information. AstraZeneca Pharmaceuticals LP; 2021. 6. Effient® (prasugrel). Prescribing information. Eli Lilly and Company; 2019. 7. Benjamin EJ, Muntner P, Alonso A, et al. Heart disease and stroke statistics—2019 update. A report from the American Heart Association. Circulation. 2019;139(10): e56-e528. doi:10.1161/CIR.0000000000000659 8. American Stroke Association website. https//www.stroke.org/en/life-after-stroke/preventing-another-stroke. Accessed June 3, 2021. 9. Packard KA, Hilleman DE. Adherence to therapies for secondary prevention of cardiovascular disease: a focus on aspirin. Cardiovasc Ther. 2016;34(6):415-422. doi:10.1111/1755-5922.12211 10. Gu Q, Dillon CF, Eberhardt MS, Wright JD, Burt VL. Preventive aspirin and other antiplatelet medication use among U.S. adults aged ≥40 years: data from the national health and nutrition examination survey, 2011-2012. Public Health Rep. 2015;130(6):643-654. 11. Weisman SM, Graham DY. Evaluation of the benefits and risks of low-dose aspirin in the secondary prevention of cardiovascular and cerebrovascular events. Arch Intern Med. 2002;162(19):2197-2202. 12. Gaziano JM, Brotons C, Coppolecchia R, et al. Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial. Lancet. 2018;392(10152):1036–1046. doi:10.1016/S0140-6736(18)31924-X